How to predict ESBL BSI (part 2)

A month ago (April 11) I blogged on the difficulties in predicting the presence of ESBL-producing bacteria as a cause of infection at the time antibiotics must be started. Wouter Rottier (PhD student) developed 2 prediction rules (for community-onset and hospital-onset infection), that seem to do better than current guideline recommendations (especially for reducing unnecessary carbapenem use). Another PhD student (Tim Deelen) now wants to validate these rules, globally. The “crowd-funding study approach” worked and sites across the world joined us…. Continue reading

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Christmas 2014 Update

Christmas lights

Now that you have digested your Christmas turkey, I thought that it would be a good time to send out an update. These articles have been posted since the last update:

I’m in a rather reflective mood, so time to remind you of some of the key themes from 2014: Ebola, MERS-CoV, universal vs. targeted interventions, faecal microbiota transplantation (FMT), whole genome sequencing (WGS), carbapenem-resistant Enterobacteriaceae (CRE), and some interesting developments in environmental science. And what will we be still talking about come Christmas 2015? Let’s hope it won’t be Ebola, and I think that WGS will be a lab technique akin to a Vitek machine rather than subject matter for NEJM. But I think we still have ground to cover on whether to go for universal or targeted interventions, FMT, and improving our study designs in infection prevention and control. I can also foresee important studies on the comparative and cost-effectiveness of the various tools at our disposal.

And finally, before I sign off for 2014, a classic BMJ study on why Rudolf’s nose is red (it’s to do with the richly vascularised nasal microcirculation of the reindeer nose, apparently).

Image: Christmas #27.

Autumn 2014 Update

 

Autumn NY 2014It’s been another busy quarter on the Micro Blog, with posts on Ebola, coverage of Infection Prevention 2014, and updates on multidrug-resistant Gram-negative rods (especially CRE):

As ever, if you have any questions, fire away. We love the interaction!

Image credit: ‘Autumn in New York’.

Summer 2014 Update

summer 2014

It’s been another busy quarter on the blog, with some updates from ECCMID and APIC, the inaugural ‘Journal Roundup’ plus a few key studies.

Please keep your responses coming – and let me know if you’d like to contribute a guest blog!

Photo: ‘Summer’ by Matteo Angelino

2014 Spring Update

Easter Bunny

It’s been a busy quarter on the blog; please see below for the blog posts since the Christmas update (which now seems like a long time ago!).

The SHEA and HIS/IPS spring conferences provided much food for thought. Also, I was delighted to host a guest blog from Prof Sally Bloomfield on What do we mean by ‘cleaning’ and ‘disinfection’?, which prompted some fascinating discussion. If you’re interested in contributing a guest blog, these are always welcome, so please let me know.

Thanks as ever for the comments – please do keep them coming.

Regards

Jon

Photo credit: ‘Easter Bunny’ by Jimmy Hilario.

A Belated Christmas Stocking

Christmas Eve MagicIf your Christmas Stocking disappointed, perhaps we can help. There were loads of fascinating articles published during 2013 that I had on my list to cover on the blog, but just ran out of time. So, rather than letting them fall into the ether, I thought I’d point you in their general direction!

New and novel aspects of environmental contamination:

Which interventions work to control hospital transmission?

Other:

Photo credit: Bo Insogna.

Christmas 2013 Update

Christmas presentsWelcome to the Micro Blog Christmas 2013 Update! These articles have been published since the last update:

It’s been an enjoyable last few months on the blog, with lots of comments and discussion, so thank-you for those; we do enjoy the interaction. In fact, the recent post on whether hospitals should provide single rooms for all patients has received a record number of comments!

Thank-you in particular to our guest bloggers, Rodney Rohde and Carolyn Dawson. Look out for more guest bloggers in 2014, and if you’re interesting in contributing to the blog, just let us know.

Micro Blog is now on Facebook, so if you like it, please ‘like’ it, if you like.

Finally, we do hope that you have a Merry Christmas and an enjoyable New Year.

See you in 2014.

Jon and Saber.

Photo credit: allerleirau.