Survey: how do you feel about the future of AMR?

I am doing a talk in Portugal later this week covering the nine decades of antibiotics since Fleming’s discovery in 1928. The last part will be about how the next decade of AMR looks globally – I’d like to know how you’re feeling about this so thought I’d run a quick poll.

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Breaking the GLASS shroud around the global AMR crisis

WHO have published the first report of the Global Antimicrobial Resistance Surveillance System (GLASS) network. GLASS was launched a couple of years ago to try and address the massive black hole in our knowledge of global AMR resistance rates. The extensive report details progress to date, focussing on which countries have established surveillance systems, and how the initial data looks (which you can also view via an online database).

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ESPAUR Report 2017: two steps forward, one step back

The next iteration of the annual ESPAUR report has been published. It’s a comprehensive, epic tome (almost 200 pages, plus an online appendix if that’s not enough for you!) so, I’ve summarised a few key points here – but the whole report is well worth a read. The number of Gram-negative BSIs is increasing (and we don’t know why); overall antibiotic prescribing is down driven by GP reductions; there’s a small increase in antibiotic prescribing in hospitals overall but early success in reducing broad spectrum agents (pip/tazo and carbapenems); and the results of the national PPS are out!

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What makes a tweet fly at conferences?

A study just published in ICHE investigates tweeting activity at several IPC / ID / AMR conferences (the 2016 editions of IPS, ID Week, FIS/HIS, and ACIPC). Perhaps the most interesting finding is that including a weblink or tweeting on certain topics (including C. difficile and the media) increase the chances of a tweet being retweeted, whereas, surprisingly, including a picture reduces the changes of a tweet being retweeted.

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More coffee = less AMR?

This one is for lovers of the brown stuff (no, the other brown stuff). I was taken by a large impressive epi study published in AIM showing that coffee consumption is associated with reduced all-cause mortality. Part of this seems to be tied up in a modified inflammatory response. Whilst the study didn’t mention infection specifically, clearly infection and inflammation are closely linked. So, this got me to asking whether anybody has looked at coffee consumption and infection / AMR outcomes?

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Money makes the AMR bugs go round in Europe? A reflection from ECCMID 2017

 

If you pick an AMR bacterium of your choice, go to EARS-Net and plot prevalence across Europe, in most cases you’ll see a rough ‘north-south’ divide, with northern European countries doing better than southern European countries in terms of AMR rates (e.g. see below for antibiotic-resistant K. pneumoniae). What is driving this difference in AMR rates? A session at this year’s ECCMID asked just that question, hypothesising that weather / climate, economics, patient mix, or culture explain the difference. It was a fascinating session, so I thought I’d share some highlights!

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