Omicron COVID-19 harm and winter IPC strategy

We have just published an evaluation of Omicron COVID-19 harm as a research letter in the Journal of Infection. This multicentre study reported the findings of a retrospective review of 129 patients with healthcare-associated Omicron COVID-19, and found that the harm profile was very different to previous waves: a small proportion of patients required supplemental oxygen, escalation to critical care, had an extended length of stay, or died from COVID-19. This informs our winter IPC strategy: whilst COVID-19 is more than “just a cold”, the balance between direct and indirect harms from COVID-19 has shifted towards preventing indirect harms (like reduced hospital throughput and delayed diagnosis) and more of a focus on other issues (e.g. flu, Gram-negative BSIs etc).

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COVID-19 ain’t what it used to be

As the COVID-19 pandemic has swept through various epidemic waves each characterised by a different variant, the trend has been towards more transmissibility but less virulence of SARS-CoV-2. The emergence of the Omicron variant continued this trend, and we are now seeing some data to compare the clinical outcomes of COVID-19 with other variants. A huge Lancet study (1.5m patients!) demonstrates clearly that the risk of hospital attendance, hospitalisation, and death is significantly lower with Omicron compared with Delta. This is important because the consequences of SARS-CoV-2 acquisition are an important factor in deciding on our management strategy – as a hospital group and in general.  

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