Hydrogen peroxide vapour vs. aerosol


There has been an awful lot of discussion out in the field about various hydrogen peroxide systems used for “no-touch” automated room disinfection. Comparison of different systems through assessment of individual studies is tricky because different methods are used to assess the effectiveness of the products. Thus, the only way to get an accurate comparison of different technologies is through head-to-head comparisons.

A recently published study compared a hydrogen peroixde vapour (HPV) system (Bioquell) with an aerosolised hydrogen peroxide (aHP) system (ASP Glosair). The independent study was performed by researchers at St. Georges’ Hospital Testing was performed in a 50m3 room with a 13m3 anteroom, representing a single occupancy room with bathroom. For both systems it was found that rooms must be sealed to prevent leakage and room re-entry must be led by a hand held sensor to ensure safety. HPV generally achieved a 6-log reduction of spore BIs and in-house prepared test discs inoculated with MRSA, Clostridium difficile and Acineotbacter baumannii, whereas aHP generally achieved a 4-log reduction or less. The aHP system had reduced efficacy against the catalase-positive A. baumannii with a <2-log reductions in the majority of room locations. HPV was able to penetrate soiling more effectively than aHP and uneven distribution of the active agent within the enclosure was evident for aHP but not for HPV.

It is difficult to produce a laboratory challenge that is truly representative of field conditions, but the authors did a thorough job and used several different ways to measure the efficacy of the products, concluding that ‘the HPV system was safer to operate, slightly faster and achieved a greater level of biological inactivation than the aHP system.’

Article citation: Fu TY, Gent P, Kumar V. Efficacy, efficiency and safety aspects of hydrogen peroixde vapour and aerosolized hydrogen peroixde room disinfection systems. J Hosp Infect 2012; 80: 199-205.


2 thoughts on “Hydrogen peroxide vapour vs. aerosol

  1. Sorry to drift off topic, but we are facing insurance claims for raccoon droppings in residential attics which, from what I’ve read, have about a 70% chance of containing Baylisascaris roundworm eggs. Currently there’s nothing but heat as a treatment. Anyone studying HPV or aHP on these?

    Based on about 10 infections per year in the US, usually children ingesting them outdoors, this is probably a ridiculous level of caution, but if insurance wants, we will investigate and write a remediation plan.


  2. Thanks Jeff. Unfortunately, I suspect that neither hydrogen peroxide vapor or aerosol would be effective for the inactivation of roundworm eggs, though I am not aware of any research. Also, the domestic application of “no-touch” decontamination methods is challenging though not impossible, as illustrated by this paper. http://www.jstor.org/stable/10.1086/507966 I think exploring preventative measures (like keeping raccoons out of residential attics) would be most effective!


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