The antibiotic course has had its day?

Schermafbeelding 2017-07-27 om 10.19.00

In a recent BMJ article, Llewelyn et al. argue that the old dogma of completing a prescribed course of antibiotics to prevent antibiotic-resistance is a myth, not based on evidence.  Actually the opposite, namely taking antibiotics for longer than necessary, increases the risk of resistance.

While I love breaking down old dogmas  (we actually had a poll on this topic some time back), many of today’s papers in the Netherlands (and I am pretty sure elsewhere, too) misinterpret the study, by slaughtering the message to patients to “always complete the full prescription”.  One of the Netherlands most influential newspapers the Volkskrant, already wrote: “Finishing antibiotic course? Nonsense.”

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It’s time to ban colistin in food animals

Guest blogger, Prof Peter Collignon (bio below) writes…

EU proposals on colistin use in food animals are just restrictions. Why not a ban?

We are now in a situation around the world where rising levels of resistance means that for many life-threatening infections with Gram-negative bacteria such as E.coli, the only effective antibiotic is now IV colistin. Colistin (polymyxin E) is an old drug that has been resurrected for use because there are no other alternatives available – even though it has major renal and neural toxicities.

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