As we all enjoy Infection Prevention Week for 2025, I thought I’d take a look into the literature to see whether anybody has done some cost-effectiveness work for an IPC service as a whole. I came across this “Umbrella” review (i.e. a review of reviews!), which looks at the cost-effectiveness of interventions to tackle HCAI and AMR (to include IPC, AMS, diagnostic stewardship), and thought it was worth sharing. The bottom line: there’s a lot of cost-effectiveness evaluations for IPC interventions, most of which are cost-effective, but a bit of a gap around cost-effectiveness of the service as a whole.