There’s a plethora of guidelines for MDR-GNR. But how do we choose between them? And how do we implement them effectively in our hospitals? I did a talk on this recently in London, here:
I’ve also done an update on the update of my comparison of CPE prevention and control guidelines, summarised below:
Blue square = recommended; Orange square = not recommended; Blank = not mentioned or no recommendation.*ESCMID guidelines did not include CPE specifically, but did include recommendation for MDR K. pneumoniae, which are included here as a proxy for CPE because the guidelines also included separate recommendations for ESBL-E.
Key changes from the last version:
- I’ve distinguished between patient skin and gastrointestinal decolonisation. This has been quite insightful, and has highlighted some more differences in the guidelines. The CDC (2015), ESCMID (2014), and ECDC (2017) CPE guidelines take a fairly favourable view towards skin decontamination using chlorhexidine, especially during outbreaks. However, the PHE (2013), Scottish (2016), Irish (2014), UK working party (2016), and Australian (2017) guidelines recommend against attempting to decolonise / decontaminate the skin, because the gut is the source of colonisation.
- Most importantly, the colour scheme has changed; it was red/green but it’s been pointed out to me that some people are red/green colour blind. So it’s become a (much more attractive) blue / orange!